GALILEO by Intel®. Honestly taken from here (https://www.ema-eda.com/sites/ema/files/Constraint%20Management.zip) and maintenance of the developed electronic product.
There will be no secret knowledge or revelations. I will just describe a number of tricks that help save a little time on debugging and a little more of your own nerves. All this separately, obviously, can be found on the net in one form or another.
All of the following is by no means the ultimate truth, but just the private professional opinion of the author.
And further. If you recognize only EPSN-40, solid rosin and soldering fat, apply sealant sausages with your hands and trace in the sprintlayout, most likely some tips and ideas will not work for you, so feel free to skip them and do not waste your time and nerves on proving that that everything works anyway.